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Malawi clinic at forefront of paediatric AIDS care

One of Africa’s first modern clinics specialising in the treatment of children living with HIV/AIDS opened in Malawi this week. Malawi Health Minister Marjorie Ngaunje said the new Baylor College of Medicine International Paediatric AIDS Initiative would spell hope for the estimated 83,000 Malawi children now living with HIV/AIDS. Read more here.

Also this week, Malawi’s National Aids Commission reported that statistics for HIV/AIDS prevalance in 2007 was 12% - down from 14% in previous years.

Malaria nets

Andrew Conte, a young Canadian aid worker, reflects on the challenges of distributing malaria prevention bed nets in Sierra Leone in 2006We are very grateful to Andrew for sharing his experience.

In 2006, I mediated the planning, marketing and distribution of one million bed nets in Sierra Leone. Funded by the World Bank and Global Fund, there were enough bed nets supplied to cover nearly 20% of the country`s population and were distributed at no cost to beneficiaries concurrently with a measles immunization campaign targeting children under 5 years.

Where we successful? Did malaria infections decrease because of increased bed net use?

It’s difficult to say.

Prevalence rates for malaria in Sierra Leone did not exist prior to the campaign, nor has any vital population health data on malaria in Sierra Leone been reported since.

Historically, donors conduct follow-up household surveys a few months after bed net distribution occurs - but this data is never made readily available. I had occasion to observe one survey from Niger that reported less than 20% of inventory (2 million bed nets) distributed being retained by households and used as intended.

With global malaria infection rates reported to range from 300 to 500 million annually - the uncertainty of these estimates measured by the W.H.O. is also never reported. And despite our advanced knowledge of the epidemiology of malaria, there is a cloud of apathetic ambiguity that has engulfed present day malaria control and disease management practices.

 

A young Sierra Leonean with a malaria net

According to a recent article in the Journal of the American Medical Association entitled Global Malaria Control in the 21st Century: A Historic but Fleeting Opportunity (co-authored by Dr. Richard Feachem, former Executive Director of the Global Fund ), one of the latest exemplary successful management practices in malaria control has been bed net distribution campaigns (funded by the Global Fund of course) because of their efficacy in increasing bed net ownership.

In an environment where humanitarian organizations distribute goods for free, what does bed net ownership mean exactly?

How and when was ownership measured from that instant the bed net was handed over to mother and child? - Where coincidentally, the camera was also poised for a donor’s photo opportunity and a self-predicated success story for the fora of international public health.

Does bed net ownership imply proper behaviour change for bed net use in Sub-Saharan Africa, or any usage at all for that matter?

One must remember - the demographics whom these campaigns are targeting reside in rural areas of developing countries with tropical climates where very little technology, infrastructure and educational outlets exist.

The learning and acclimatization that must occur in order for the introduction of bed net technology to have a lasting effect on preventing malaria infection, such as hanging, education, and behaviour change, extends far beyond the term “ownership” - especially when given to beneficiaries for free.

Yet the rhetoric used by UN and Development agencies is common place. They report their (public tax) dollars (donated from Western countries) spent on aid interventions, and units donated to countries on massive scale - purchased from (Western) private suppliers that operate in monopolized markets - all which predicate irrelevant disease outcomes for those children in Sub-Saharan Africa, who are often carried by their mothers to health centers because they are infected by malaria with symptoms undetected, prevention unknown.

It’s time to break this cycle of carelessness.

Update from Selkirk

Have a look on the Project photo page to see new photographs of staff and patients at Selkirk Medical Practice in the Scottish Borders. Of particular interest are pictures of the ‘Baby Massage Clinic’ for new mothers and babies run by Practice Health Visitor, Rois Henderson. 

The Practice is twinned with Chileka in Blantyre, Malawi. Dr John Gillies from Selkirk is currently teaching a family medicine course in Malawi and plans to visit Chileka.

Patients photographed have given their consent for picutres to be shown on the Project site.

Mobile phones for global health

Following on from the blog post about how mobile phone text messaging has been used to support drug de-toxification in Dundee, readers of the Malawi Clinics Blog may be interested to learn that the United Nations and Vodafone have joined together to release a report entitled Mobile Technology for Social Change : Trends in NGO Mobile Use. The Report examines eleven case stutdies in ‘mobile activism’ and includes some interesting health-related projects including:

- Mobile health data collection systems in Kenya and Zambia

Collecting and tracking essential health data on handheld devices, in countries where statistical information was previously gathered via paper and pencil, if recorded at all.

- Monitoring HIV/AIDS care in South Africa

Using mobile devices to collect health data and support HIV/AIDS patient monitoring in a country with the world’s highest HIV/AIDS infection rates, and where rural populations often otherwise go unassisted.

- Sexual health information for teenagers

Connecting young people in the US and UK to important information on sexual and reproductive health via anonymous text messaging, to empower young people to make informed sexual health decisions.

- Continuing medical education for remote healthcare workers in Uganda

Providing medical updates and access to vital information via mobile phones for doctors and nurses working in some of the most destitute regions, where continuing medical education services are lacking.

MRSA and overuse of antibiotics

What is MRSA?

MRSA stands for methicillin-resistant Straphylococus aureus but is shorthand for any strain of this common bacteria that is resistant to one or more conventional antibiotics. MRSA is not completely resistant to antibiotics but patients may require a much higher dose over a much longer period, or the use of an alternative antibiotic to which the bug has less resistance.

What are the symptoms?

MRSA infections can cause a broad range of symptoms depending on the part of the body that is infected. These may include surgical wounds, burns, catheter sites, eye, skin and blood. Infection often results in redness, swelling and tenderness at the site of infection. Sometimes, people may carry MRSA without having any symptoms.

What is the link with hospitals and clinics?

The reason that hospitals and clinics seem to be hotbeds for resistant MRSA is because so many different strains are being thrown together with so many doses of antibiotics, vastly accelerating this natural selection process.

Prevention

Rigorous cleaning with warm water and detergent between patients is the most effective means of removing spores from the contaminated environment and the hands of staff, say experts. One of the main reasons that bacteria evolce into “superbugs” is the overuse of antibiotics, both in human and veterinary medicine. Until recently, patients visiting their doctor in Scotland with a viral infection might demand, and be given, an antibiotic prescription - despite the fact that antibiotics have no effect on this and may even strengthen the communities of bacteria in their bodies. Doctors have now been told to cut antibiotic prescribing.

Learning from Africa

Does the Malawian reliance on nursing staff for the treatment of most patients and the emphasis at clinics on professional hierachy and traditional nursing ‘matrons’ to manage wards offer lessons in the importance of hygiene and attention to detail for Scotland? Will the reality of a shortfall in the ready availability antibiotics and other medicines in Malawi lessen the effects of so-called superbugs? Share your thoughts on the blog.

Malawi nursing students demonstrate their starched white uniforms

Further sources of information on the web

The dangers of MRSA and Clostridium difficile

(Guardian Newspaper)

video clip with Q+A

(YouTube)

Health-care workers: source, vector, or victim of MRSA?

(The Lancet)

Infection control in paediatrics

(The Lancet)

Outreach - finding low-key solutions

Practice nurse Amiko Hippisley remembers working with limited resources in a rural setting near to Dedza in Malawi last summer:

“When we were working in Kaphuka Clinic (rural hospital) last July, some of the doctors did an outreach clinic about 5 kms away (for patients who can’t walk the distance to the clinic).  They did consultations, diagnosing & prescribing of medications all morning.  It was only on the return to the clinic that it was realised that the SP malaria tablets had been decanted by one of the staff into an old antibiotic container, and so all the patients who’d been prescribed antibiotics that morning had actually been given malaria treatment instead.  The clinic staff were quickly advised about not decanting medications into different containers, and if necessary to do this, to label the containers very clearly!  (Better this way round than the other as a lot of patients have malaria anyway.)

There is such a shortage of tablet containers and when we helped out in the pharmacy, we had to wrap up bundles of 5 malaria tablets into torn up bits of scrap paper.”

Prevention - travel advice at Scottish GP practices

The Practice Nurse at Stockbridge Blue Practice in Edinburgh, Scotland, (twinned with Ndirande in Blantyre, Malawi) regularly gives malaria prevention advice to patients travelling to malaria high-risk countries. Twinning Project team member, Jemma, consulted Amiko Hippisley before visiting Malawi in November. In this post, Amiko reviews routine procedure.

“Regarding our antimalarial advice we give to patients, I’ve learned as I’ve gone along but also use the Travax Travel health web-site for professionals (www.travax.scot.nhs.uk), which is done by SCIEH, based in Glasgow and updated daily (you need an ID & password).  Their sister travel web-site for the public is www.fitfortravel.scot.nhs.uk, which I give out to patients.  They are easy to use, with an A-Z index, so you click on the country and then click on ‘malaria map’ which gives a key guide, as antimalarial prophylaxis can vary within a country, depending on which region.  www.malariahotspots.co.uk is also a very useful and easy to use web-site for the public & health professionals.

Our patients fill out a travel form prior to their appointment and they get a single, double or triple appointment, depending on how many vaccines they need and how many countries they’re visiting for antimalarial advice and prescription.  The PN goes through the patient’s notes and computer records to see what vaccines they’re up-to-date with and which ones or boosters they need, prior to seeing the patient. I have Travax up on the screen during the consultation, as it’s better for the patient to visualise the country & malarious areas for their travels.

If they only need OTC (over the counter) tablets - chloroquine (daily) and/or proguanil (weekly), they are advised to buy them from the chemist.  They don’t need to remember the name/s, as the pharmacist will know what tablets are required.  I advise that proguanil can cause some patients to feel a bit nauseous but that’s better than contracting malaria. If they need a private prescription, which we charge £14.00 for (prescription & admin charge), we write them out for the patient but the GP signs it.  They are advised of the ‘double charge’, as the patient then needs to buy the tablets from the chemist also.

The OTC tablets are not effective in areas where the private tablets are required but the private tablets will also work in the areas where OTC tablets are needed.  This is due to the malaria resistance in the mosquitos in the milder areas.

The 3 choices of private tablets are:-

1. Malarone (atovaquone/proguanil), which is the most favoured because it has the least side-effects and is needed for a much shorter time.  It is a daily tablet, that is taken from 1-2 days before entry in to the malarious area, daily whilst there & then for a week after leaving the area.  They are the most expensive option.  Cost ~£1.60 per tablet.  It is the newest tablet to the market but has been out many years now.  Licensed for 36 days but can be prescribed for up to 6 months, if required.

2. Doxycycline 100 mg tablet.  Also daily but taken from about a week before, during and for a month after.  The benefit is that it is a broad spectrum antibiotic but has the side-effect of interfering with the pill and also causes skin photosensitivity.  High SPF is advised.  It can aalso cause oesophagitis/gastritis in some cases, so needs to be taken with a good amount of food or after meals!  Prices for this one vary a lot from chemist to chemist, so it’s worth shopping around!  Licensed for 3 months but can be prescribed for much longer.

3. Mefloquine/Lariam.  This costs about the same as malarone but is a weekly tablet, so works out a lot cheaper.  It potentially has the worst side-effects (neuro-psychiatric) and there’s a lot of scare-mongering about it but it only affects about 15% of people.  Can be prescribed long-term.

When prescribing these, we need to take in to account things like allergy to certain components of the tablets, epilepsy, contraception use, pregnancy, mental history, other medical conditions, etc. We always have to be on our toes so as not to make a mistake.

Prevention - NGO advocacy

US based charity ‘Africa Fighting Malaria‘ (AFM) has created an interactive map of Africa to indicate which countries are conducting ‘Indoor Residual Spraying’ (IRS) along with the main funders.

Project Director, Richard Tren, commented that: “World Malaria Day 2008 focuses on malaria across borders – and some of the best cross-border malaria control programs rely heavily on IRS.”

The AFM website also has some interesting sources of further information for those keen to learn more:

- Lessons from other nations in malaria fight

- World Malaria Day - just another PR swat at malaria?

- Uganda: DDT sprayed in Oyam

Treatment - patient autonomy in record keeping prompts action

Student nurse, Dennis Kalimbira, recounts his personal story of a contracting malaria and seeking treatment:

Dennis Kalimbira - First Year Student at MCHS, Zomba Campus

I was with my friend Saul going to Zomba Central Hospital in the southern part of Malawi. I complained of fever, rigors, headache and joint pains. My friend suggested that I go and see a clinician. So reluctantly I went.

After hearing how I felt, the clinical officer wrote something in my Health Passport and sent me to the laboratory for malaria parasites test. The outcome of the test was positive. Then I went back to the clinician. He prescribed a new drug being used in Malawi, commonly called LA. Luck was on my side. After three days I was on my feet to resume attending my clinical practicals.

This malaria bout prompted me to look at my past medical history. Guess what I found? My Health Passport records that I suffered from malaria more than any other disease.This experience hurried me to study about the disease. I remember I asked myself questions: What is malaria? Why is it the problem here in Malawi and what should be done to reduce the incidence?

So I had a lot to learn about the disease and its impact on public health. Malawi lies in the tropics which is usually hot. Explanation has it that the parasite finds its way into mosquito gut after being ingested by a mosquito while having a bloody meal. There it undergoes a life cycle transformation after which the parasite migrates back to the mosquitoes salivary glands where it can be injected into another victim. The eye catcher is this; the life-cycle change called sporogony, takes about two weeks. If the mosquito dies before sporogony is completed, the mosquito never becomes infective. The central ecological point is that the warmer the temperature, the faster the sporoogny and the likely it is that the mosquito will live to become infective. Mosquito life-span is about two weeks. So malaria is a tropical disease and Malawi being within it and oftenly hot is likely to have high incidence.

Other findings established that poverty, HIV/AIDS, high population, knowledge deficit about the disease and parasite resistance to anti-malarials are other causes of high incidence.

Poverty makes it difficult to adopt the measures that can cut malaria transmission route. Impoverished familiesfind it hard to spray their homes with insecticides; they can not afford to install screens in doors and windows to keep away mosquitoes and buy insecticide-treated mosquito nets. Malaria itself exacerbates poverty by diverting people’s productive time as citizens absent themselves from work to attending funerals form malaria deaths, sick relatives and family members are themselves falling sick as I did. Children who frequently fall sick do not do well in school due to persistent absenteeism. This leaves impoverished households without financial means to fight the disease.

HIV/AIDS has played a big role in increasing malaria incidents since the immunocompromised bodies do not withstand against malaria parasites.

The number of people per household determines the living conditions and distribution of things. Most families having many children find it hard to buy mosquito nets for all household members and to live in a decent environment as most populous households live below poverty line.

Knowledge deficit related to the disease process makes people seek traditional healing interventions when sick since they feel they are bewitched and this diverts their interest to take part in malaria fight by preventing themselves from a mosquito bite and receiving treatment in hospitals.

Another thing is that malaria is diagnosed in a laboratory in district and central hospitals. Many people living in rural areas are diagnosed clinically which creates a chance of giving medicine to people who do not have malaria hence the parasite resistance to antimalarial.

So What can We Do?

It’s not easy to say what can be done since there are already interventions in place but we still have high incidences. Probably we should continue promoting for insecticides-treated net use every night to prevent ourselves from an anopheles mosquito bite. Advocate reduction of prices of mosquito nets so that they are affordable to most households and continue re-treatment campaigns. There has to be a conducive environment for families’ earnings to grow so that they can afford to protect themselves by buying and treating nets and live in a conducive environment. Ways should be promoted that they will make families to have manageable households. The fight against HIV/AIDS should be gallantly fought, to prevent transmission. Screening of malarial parasites should also be taking place in rural health facilities. Information, Education and Communication should be advocated so that people have knowledge of malaria and take part in the fight.

Now as we celebrate Malaria World Day, we should not simply be standing-by while millions of lives are lost each passing day due to preventable, curable malaria. The mosquito whine should always remind us that it’s time we fight malaria not to just stare at it. I tell you we cannot afford to stare while people are groaning with pain in hospitals.”


Diagnosis - cultural beliefs and modern medicine

Here is another Malawi student perspective on the effects on malaria in Malawi which the author has entitled ‘Malaria Versus the Innocent Child’:

“Malaria is a killer - a FACT!  Death from malaria is very avoidable - another FACT! The list can go on and on. There are more facts about malaria than the effects the world is employing on the ground in the fight against malaria. More children, innocent, I can say, are dying every minute in very disturbing and sad circumstances. From the mere ignorance of malaria existence, to the poor hospital treatment seeking behaviour, all the way to improper treatment has made malaria the untouchable monster claiming the lives of innocent children. Malaria is killing adults at an alarming rate as well, but it’s the child who dies more innocently.

Malaria is a disease caused by protozoa that attacks the blood system and is treatable, simple! This is the message that ought to be carried to the multitude of parents and guardians looking after children The scenario we have is of parents seeking treatment from as far as herbalists when the signs and symptoms clearly show it is malaria. In the end we have children who are dying in the homes and villages and not from malaria but some ailments caused by witchcraft, according to the parents. Medical experience has shown that children respond very quickly and positively to medication. With such a background , the knowledge of malaria as an end product of an infectious mosquito bite will mean prompt treatment hence avoiding death.

And there is this group of people which knows malaria from all angles and what do they do? A child would be sick with malaria signs and symptoms but the guardians still want to prove beyond any reasonable doubt that it is malaria and not something else. How? Nobody knows. In the end , guardians turn up at a hospital with a child who is almost dead of malaria and expect the medical practitioner to perform some miracles and rescue the innocent child. It’s almost impossible. The child will be put on medication but it will be too late, the child dies. Who is to blame?

Fine! A child is sick and the guardian rushes to the hospital. The signs and symptoms show it might be malaria. But wait, there is this medical practitioner who is researching on the widely researched topic at a very wrong time with probably no objectives. The diagnosis given is something else just as the medicine given. The response is poor and now everybody thinks let’s try malaria treatment when the child is on a life saving machine. Can this work?

As the world is commemorating World Malaria Day, let us ask ourselves the question as at what level are we fighting malaria and with what progress? Health Education to the general community about malaria, promotion of prompt hospital treatment seeking behaviour and standard effective treatment of malaria would be a very reasonable way to go in this noble fight.”

Chandulo Kayira-Year 3 Nursing & Midwifery Technician Student at Malawi College of Health Sciences-Zomba Campus